PYC Therapeutics Limited (ASX: PYC) - ETF Exposure

- Current share price for PYC : $1.780

PYC Therapeutics (PYC) is an ASX-listed company and is held by a number of exchange traded funds (ETFs). It is a clinical-stage biotechnology company creating a new generation of RNA therapies to change the lives of patients with genetic diseases. The Company utilises its proprietary drug delivery platform to enhance the potency of precision medicines within the rapidly growing and commercially proven RNA therapeutic class.

PYC General Information ⁺

ASX Code	PYC
Website	http://pyctx.com
Industry/Sector	Biotechnology
Market Cap ($M)	1,751
PYC Share Price	$1.780
Day High	$1.830
Day Low	$1.703
Last Close	$1.780
PYC Share Price Movement	- ( No change )

Prices as at 16:40, 23 Oct 2026

⁺Security prices are delayed by at least 20 minutes and are indicative only.

Already own an Australian ETF? You may already have meaningful exposure to PYC

As a significant Australian company by market capitalisation, PYC is held across 5 ETFs spanning strategies that include biotechnology exposure . Its weighting in those funds means performance can have an outsized influence - when PYC moves, funds like ISO, SSO, VSO, VAS and A300 that hold it can move with it.

For more concentrated exposure, ETFs such as ISO (iShares S&P/ASX Small Ordinaries ETF Index Fund) allocate about 0.5% to PYC , while the average exposure across all 5 ETFs that hold it is around 0.3% .

Top ETF holdings

iShares S&P/ASX Small Ordinaries ETF Index Fund (ISO) ~ 0.5%
State Street SPDR S&P/ASX Small Ordinaries ETF (SSO) ~ 0.5%
Vanguard MSCI Australian Small Companies Index ETF (VSO) ~ 0.3%
Vanguard Australian Shares Index ETF (VAS) ~ 0.1%
Global X Australia 300 ETF (A300) ~ 0%

Last updated: ETF data and holdings as at 25 October 2026

Own PYC directly or through an ETF?

How does holding PYC Therapeutics Limited (PYC) shares directly compare to ETFs that include it?

	PYC Direct	ISO ASX	SSO ASX	VSO ASX	VAS ASX	A300 ASX
Holdings	1 company	219 holdings	219 holdings	204 holdings	334 holdings	312 holdings
PYC Weight	100%	0.5%	0.5%	0.3%	0.1%	0%
Diversification	Single Stock	Broad	Broad	Broad	Broad	Broad
Annual Cost	Brokerage only	0.55% p.a.	0.5% p.a.	0.3% p.a.	0.07% p.a.	0.03% p.a.
Approx. Yield	0%	4.78%	10.15%	5.07%	3.18%	3.06%
Star Ratings	-

Yields and costs are approximate. ETF yields reflect the fund's dividend distributions, not PYC's direct yield. Annual cost uses each ETF's MER.

PYC Exposure on $10,000 investment

How a $10,000 investment in PYC Therapeutics Limited (PYC) one week ago compares with ETFs that hold it.

Security	Investment type	Current price	7-day price movement	Dollar change	Value today
PYC Therapeutics Limited (PYC)	Direct share	$1.780	-6.81%	-$681	$9,319
iShares S&P/ASX Small Ordinaries ETF Index Fund (ISO)	Equity - Australia Small/Mid Cap	$4.570	-4.19%	-$419	$9,581
State Street SPDR S&P/ASX Small Ordinaries ETF (SSO)	Equity - Australia Small/Mid Cap	$13.220	-3.99%	-$399	$9,601
Vanguard MSCI Australian Small Companies Index ETF (VSO)	Equity - Australia Small/Mid Cap	$68.910	-2.81%	-$281	$9,719
Vanguard Australian Shares Index ETF (VAS)	Equity - Australia	$108.570	-0.27%	-$27	$9,973
Global X Australia 300 ETF (A300)	Equity - Australia	$51.140	-0.49%	-$49	$9,951

Assumes $10,000 invested 7 days ago. Figures are based on price movement only and exclude distributions, fees and brokerage.

PYC Therapeutics Limited (PYC) ETFs

5 ETFs hold PYC Therapeutics Limited (PYC).

ETF	PYC Weight	MER	Yield
iShares S&P/ASX Small Ordinaries ETF Index Fund (ISO)	0.5%	0.55%	4.78%
State Street SPDR S&P/ASX Small Ordinaries ETF (SSO)	0.5%	0.5%	10.15%
Vanguard MSCI Australian Small Companies Index ETF (VSO)	0.3%	0.3%	5.07%
Vanguard Australian Shares Index ETF (VAS)	0.1%	0.07%	3.18%
Global X Australia 300 ETF (A300)	0%	0.03%	3.06%

PYC Therapeutics Limited (PYC) Upcoming Dividends & Yields

Distribution Type	Dividend	Franking	Ex-dividend date	Payment date	Current Price⁺	Price 7D Avg	Dividend Yield

See all dividends from PYC Therapeutics Limited (PYC) or use our Upcoming Dividends tool to search for dividends across all ASX-listed securities.

PYC Therapeutics Limited (PYC) price-sensitive announcements

PYC - PKD Program - Presentation of Data at ASN Conference

PYC Therapeutics Limited announced that it will present exploratory efficacy data at the A

PYC Therapeutics Limited (PYC)
7 Oct 2026 | 8:42 AM

PYC - S&P DJI Announces September 2026 Quarterly Rebalance

S&P Dow Jones Indices announced on 4 September 2026 its September 2026 quarterly rebalance

PYC Therapeutics Limited (PYC)
4 Sep 2026 | 5:10 PM

PYC - Appendix 4E

PYC Therapeutics Limited’s Appendix 4E preliminary financial report for the Australian fin

PYC Therapeutics Limited (PYC)
28 Aug 2026 | 7:08 PM

PYC - Quarterly Activities/Appendix 4C Cash Flow Report

PYC Therapeutics Limited, a clinical-stage biotechnology company based in Australia, relea

PYC Therapeutics Limited (PYC)
29 Jul 2026 | 8:45 AM

PYC Therapeutics Limited (PYC) Recent ASX Announcements

Company	Sector	Market Cap ($m)	Headline	Release date/time⁺	Price at release⁺	Current price⁺	Gain/Loss
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	PKD Program - ASN Presentation	23 Oct 2026 8:21AM	$1.810	$1.780	fallen by 1.66%
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	Exercise of Options and Cleansing Notice	16 Oct 2026 1:49PM	$1.880	$1.780	fallen by 5.32%
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	Notice of Annual General Meeting/Proxy Form	12 Oct 2026 8:36AM	$2.450	$1.780	fallen by 27.35%
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	Application for quotation of securities - PYC	8 Oct 2026 1:50PM	$2.495	$1.780	fallen by 28.66%
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	Notification of cessation of securities - PYC	8 Oct 2026 1:48PM	$2.490	$1.780	fallen by 28.51%
PYC Therapeutics Limited (PYC) ORDINARY FULLY PAID	Health Care	$1,752	PKD Program - Presentation of Data at ASN Conference	7 Oct 2026 8:42AM	$2.680	$1.780	fallen by 33.58%

PYC Financial Summary

Year to Jun	NPAT	EPS	EPS chg (%)	Yield (%)	Franking (%)
2026A	-$43.77	-$5.90	-39.70%	0.00%	0.0%
2025A	-$51.01	-$9.80	5.50%	0.00%	0.0%
2024A	-$38.11	-$9.30	36.70%	0.00%	0.0%

PYC Peer Comparison

Company	Mkt Cap	EPS Growth (%)			P/E (%)			Dividend Yield (%)
Company	Mkt Cap	2024 A	2025 A	2026 A	2024 A	2025 A	2026 A	2024 A	2025 A	2026 A
CSL Limited (CSL)	$94,125M	0.7309	-0.4392	0.0602	12.1513	21.6669	20.4370	2.17%	2.17%	2.24%
Clinuvel Pharmaceuticals Limited (CUV)	$357M	-0.0696	-0.0719	0.0242	10.5838	11.4032	11.1339	0.71%	0.71%	0.71%
Mesoblast Limited (MSB)	$2,381M	-0.4501	0.0000	0.0000	0.0000	0.0000	831.8182	0.00%	0.00%	0.00%
PYC Therapeutics Limited (PYC)	$1,781M	-0.3971	0.0000	0.0000	0.0000	0.0000	0.0000	0.00%	0.00%	0.00%
Telix Pharmaceuticals Limited (TLX)	$4,649M	-1.3893	0.0000	-0.5235	0.0000	160.7059	337.2840	0.00%	0.00%	0.00%

PYC Market Comparison

	Earnings	P/E Ratio	P/B Ratio	P/E Growth
Company	0.00	0.00	2.52	0.00
Market	0.30	13.30	1.03	0.72
Sector	0.78	41.90	2.29	2.12

PYC Directors

Name	Position	Start Date
Dr Rohan Hockings	Chief Executive Officer, Managing Director	30 Nov 2018
Mr Peter John Coleman	Non-Executive Chairman, Non-Executive Director	18 Nov 2025
Professor Ian Jeffrey Constable	Non-Executive Director	21 Sep 2025

PYC Therapeutics Limited (PYC) Changes in Directors' Interest & Trades

Date of change	Director	Buy/Sell	Security Type	Qty	Trade Price	Value
24 Mar 2026	HOCKINGS, Rohan	Buy	Direct Shares	82,550	$1.210	$99,883.000
6 Mar 2026	HOCKINGS, Rohan	Issued	Direct Shares	80,010	$1.500	$120,015.000
6 Mar 2026	CONSTABLE, Ian	Issued	Indirect Shares	123,000	$1.500	$184,500.000

See all changes in directors' interest & trades for PYC Therapeutics Limited (PYC) or use our Changes in directors' interest tool to search for changes & trades across all ASX-listed securities.

PYC Management

Name	Position
Jonathan Riley	Joint Company Secretary
Stephen Ledger	Joint Company Secretary

PYC Substantial Shareholders

Under ASX rules large investors and investment funds must disclose when they own more than a 5% stake in PYC Therapeutics Limited (PYC). However, you won't necessarily see their names in the company’s annual report, as many trade under nominee names. These shareholders are obliged to provide ongoing substantial notices relating to any change of 1% or more.

Holding	Name
92,818,753 (9.44%)	RA Capital Healthcare Fund GP, LLC
84,578,385 (8.60%)	Australian Land Pty Ltd

PYC Calendar of Events

Date	Event
27 August 2027	Report (Annual)
27 August 2027	Report (Prelim)
22 February 2027	Report (Interim)

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