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Dimerix Limited (ASX:DXB)
ALERT: Price-sensitive ASX Announcement for DXB
Current share price for DXB : $0.245 -0.005 (-2%)+
Announcement
Release
23 Jul 2026 8:46AM
Price at Release
$0.250
Full Release
Summary
Dimerix Limited has successfully obtained a US patent for its new asset, DMX-652, a selective inhibitor of the mitochondrial enzyme USP30. The patent extends the composition of matter claims covering DMX-652 until April 2043, with adjustments. This compound, delivered as an oral capsule, is intended to support mitochondrial quality control in injured kidney cells, aimed at treating acute kidney injury (AKI) associated with cardiac surgery. Currently, no approved therapies exist for AKI, emphasizing the potential clinical and commercial value of DMX-652. Preparations for a Phase 2 clinical trial are underway, aiming to investigate its efficacy in preventing kidney injury and preserving renal function.
Key Points
- US patent granted for Dimerix's new asset DMX-652.
- DMX-652 is a selective inhibitor of USP30, designed to support mitochondrial quality in injured kidney cells.
- The patent provides composition of matter claims covering DMX-652 until 2043.
- DMX-652 is intended for treatment in acute kidney injury (AKI) associated with cardiac surgery.
- No current approved therapies exist for AKI, highlighting the potential impact of DMX-652.
- Phase 2 clinical trial preparations underway for DMX-652 in the initial AKI indication.
IMPORTANT NOTE: This information is autogenerated and has not been reviewed for accuracy or completeness. You should refer to the full announcement here for further information.
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